IntroductionDiabetic foot ulcers are one of the most serious complications of diabetes mellitus and are associated with high morbidity as well as mortality. They often predate amputation of the feet and / or the lower limbs and therefore have a major im pact on the quality of life of the patients and their families as well as on national health care and social systems. Management of diabetic foot lesions is complex and represents a great challenge for physicians, hospitals and health care providers and the effort is concentrating on prevention. Improved wound healing with long-term regeneration mechanisms for the affected tissue is required. With its new Spark WaveTM technology, MTS introdu-ces an innovative and highly effective treatment modality for improved wound healing in diabetic foot ulcers.
MTS Spark WaveTM Technology and its mechanism of action in wound managementSpark WavesTM are especially effective shockwaves that are electro hydraulically generated by means of a spark discharge in a water quench.
The treatment with Spark WavesTM is non-invasive, well tolerated by patients and easy to apply on an outpatient basis. The Spark WaveTM energy is directly applied onto the wound itself where it can unfold its complete healing mechanisms in any phase of the wound healing process as well as before and after amputation. No side effects have been reported yet. Spark WaveTM energy re-initiates the stagnating healing process in a sub acute and chronic state and initiates effective healing process in an acute stadium . Spark WavesTM activate a cascade of biochemical regeneration mechanisms and induce the following biological reactions on cellular level:
- the body´s own production of growth factors such as VEGF, eNOS, PCNA etc.
- the new promotion of blood vessels (angiogenesis & vasculogenesis) (Fig. 1)
- an improved blood flow (Fig. 2 ) and cell proliferation (Fig.3) as well as
- the migration of stem cells.