Background: Characteristics of chronic rotator cuff tears include continuous loss of tendon structure as well as tendon elasticity, followed by a high failure rate after surgical reconstruction. Several studies have already shown the beneficial effect of extracorporeal shockwave therapy (ESWT) on tissue regeneration in tendon pathologies. Methods: After tendon detachment and 3 weeks of […]
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Spark Wave® Therapy Improves Full Thickness Skin Defects
Skin grafting is one of the most common treatment options for permanent replacement of lost skin and proven effective in burn patients. The procedure consists of transplantation of skin or artificial dermal replacements, and in some instances underlying tissues, harvested from one anatomical location to a different location. However the ischemic insult, due to nature […]
Spark Wave® Therapy Improves Cardiac Function
Ischemic heart disease remains the leading cause of mortality (12.7 %) worldwide, causing more than 7 million deaths per year. Native angiogenesis after infarction most often is not sufficient for appropriate supply of hibernating cardiomyocytes, leading to pathologic left ventricle (LV) remodeling and ischemic cardiomyopathy, a clinical entity characterized by a poor prognosis and severe […]
Spark Wave® Therapy Ameliorates Urinary Incontinence
Stress urinary incontinence (SUI) is the involuntary leakage of urine during activities such as coughing, sneezing, lifting, laughing or excersises. SUI is estimated to affect at least 10 – 20 % of women and poses a significant health problem. Incontinence affects quality of women`s life in many ways as it limits social and personal […]
Spark Wave® Therapy – a New Method for Peripheral Nerve Regeneration
Peripheral nerve injuries affect millions of people every year. After trauma or surgery, patients often require autologous nerve grafting, which is the „gold standard“, but nevertheless a complex and demanding surgical procedure with low chances of success. The choice of graft type and optimal regeneration conditions are crucial for the final result.Scientists of the […]
Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling
In this study, d’Agostino et al. researched the effect of shock waves on macrophages in view of a possible function in tissue regeneration and remodeling. The team used two different types of macrophages: M1 pro-inflammatory macrophages and M2 anti-inflammatory macrophages. After SW treatment with different intensities the expression was measured via qPCR. The results of […]