Spark Wave® Therapy – Therapeutic Range for Regeneration

Defining a Therapeutic Range for Regeneration of Ischemic Myocardium via Shock Waves (Pölzl et al., 2021. Department of Cardiac Surgery, Medical University of Innsbruck, Austria.) Abstract Shockwave therapy (SWT) represents a promising regenerative treatment option for patients with ischemic cardiomyopathy. Although no side-effects have been described upon SWT, potential cellular damage at therapeutic energies has […]

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Spark Wave® Therapy – Identifies Strategies to Cure Premature Ejaculation

Novel Use of a Shock Wave Device for Energy Flux Density Threshold Testing of the Distal Ventral Erect Penile Shaft as a Marker of Penile Dysesthesia/Hypersensitivity Associated with Premature Ejaculation (Uloko et al., 2020. 21st Annual Fall Scientific Meeting of Sexual Medicine Society of North America (SMSNA), Abstract No.041) San Diego Sexual Medicine Introduction: Premature […]

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Spark Wave® Therapy – Accelerates Chronic Wound Healing

OBJECTIVE:  Extracorporeal shockwave therapy (ESWT) has a significant positive effect to accelerate chronic wound healing. This study investigated whether the vascular endothelial growth factor (VEGF)–related pathway has involved in ESWT enhancement of diabetic wound healing. 1   MATERIAL AND METHODS: A dorsal skin defect (area, 6 × 5 cm) in a streptozotocin-induced diabetes rodent model […]

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Spark Wave® Therapy – a Novel, Non-Invasive Approach for Stress Urinary Incontinence

OBJECTIVE:  To determine the outcomes and mechanisms of delayed low-intensity extracorporeal shock wave therapy (Li-ESWT) in a rat model of irreversiible SUI. 1 MATERIAL AND METHODS: Twenty-four female Sprague-Dawley rats were randomly assigned into 3 groups: sham control, vaginal balloon dilation + β-aminopropionitrile (BAPN; SUI group), and vaginal balloon dilation + BAPN + treatment with Li-ESWT […]

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Spark Wave® Therapy Regenerates Ischemic Myocardium

Gollmann-Tepeköylü C, Leo Pölz et al., 2019 University Clinic of Cardiac Surgery, Medical University of Innsbruck, Austria. Austrian Cluster for Tissue Regeneration, Vienna, Austria. Background: As many current approaches for heart regeneration exert unfavorable side-effects, the induction of endogenous repair mechanisms in ischemic heart disease is of particular interest. Recently, exosomes carrying angiogenic miRNAs have […]

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Spark Wave® Therapy Substantially Improves Tendon Regeneration

  Background: Characteristics of chronic rotator cuff tears include continuous loss of tendon structure as well as tendon elasticity, followed by a high failure rate after surgical reconstruction. Several studies have already shown the beneficial effect of extracorporeal shockwave therapy (ESWT) on tissue regeneration in tendon pathologies. Methods: After tendon detachment and 3 weeks of […]

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Spark Wave® Therapy Improves Full Thickness Skin Defects

Skin grafting is one of the most common treatment options for permanent replacement of lost skin and proven effective in burn patients. The procedure consists of transplantation of skin or artificial dermal replacements, and in some instances underlying tissues, harvested from one anatomical location to a different location. However the ischemic insult, due to nature […]

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Spark Wave® Therapy Improves Cardiac Function

Ischemic heart disease remains the leading cause of mortality (12.7 %) worldwide, causing more than 7 million deaths per year. Native angiogenesis after infarction most often is not sufficient for appropriate supply of hibernating cardiomyocytes, leading to pathologic left ventricle (LV) remodeling and ischemic cardiomyopathy, a clinical entity characterized by a poor prognosis and severe […]

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